Anti-Hu Tenascin C Purified, Clone: [T2H5], Monoclonal
Artikelnummer:
EXB-11-370-C100
Hersteller Artikelnummer:
11-370-C100
Alternativnummer:
EXB-11-370-C100
Hersteller:
EXBIO
Kategorie:
Antikörper
Applikation:
IHC-P, IP, WB
Spezies Reaktivität:
Human
Immunogen:
Protein preparation from a homogenate of a human mammary tumour specimen.
Tenascin C is an approximately 250 kDa extracellular matrix glycoprotein with important roles in the nervous system, as it promotes correct migration of growing axons during development and during neuronal regeneration. It is also involved in synaptic plasticity. Ligands of tenascin C are integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3, and alpha-V/beta-6. Similarly to neural cells, it also stimulates angiogenesis by promoting elongation and migration of endothelial cells.
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Klon-Bezeichnung:
[T2H5]
Isotyp:
Mouse IgG1
Puffer:
Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
Lagerung:
2°C to 8°C
Target-Kategorie:
Tenascin C
Antibody Type:
Monoclonal Antibody
Anwendungsbeschreibung:
Immunohistochemistry (paraffin sections): Immunohistochemical detection of tenascin is valuable for studies of tissue differentiation and tumour growth. The antibody T2H5 is excellent for staining of paraffin-embedded tissue sections. Heat-mediated antigen retrieval in citrate buffer.Western blotting: Recommended dilution: 1-2 µg/ml.
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