Peptide corresponding to aa 196-212 of human NTAL coupled to KLH.
NTAL (non-T cell activation linker), also known as LAB (linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Klon-Bezeichnung:
[NAP-03]
Isotyp:
Mouse IgG2a
Puffer:
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide