Anti-Hu SIGLEC10 APC, Clone: [5G6], Monoclonal

Produktübersicht

• Artikelname: Anti-Hu SIGLEC10 APC, Clone: [5G6], Monoclonal
• Artikelnummer: EXB-1A-932-T100
• Hersteller Artikelnummer: 1A-932-T100
• Alternativnummer: EXB-1A-932-T100
• Hersteller: EXBIO
• Kategorie: Antikörper
• Applikation: FC
• Spezies Reaktivität: Human
• Immunogen: SIGLEC10 extracellular domain fused with human IgG1 Fc fragment
• Konjugation: APC

Produktbeschreibung

SIGLEC10 is a CD33-related receptor of sialoglycans, expressed on eosinophils, monocytes, a subpopulation of NK cells, and at lower level on B cells. Its murine ortholog is Siglec G. SIGLEC10 seems to act as an immunomodulatory receptor, which binds to VAP-1, a glycoprotein expressed on endothelium under inflammatory conditions. Another ligand of SIGLEC10 is CD24, a marker of poorer prognosis in carcinomas.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [5G6]
• Puffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Target-Kategorie: SIGLEC10

Anwendungsbeschreibung

• Anwendungsbeschreibung: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.