CD273 / PD-L2 (programmed death ligand-1), also known as B7-DC, is a member of the B7 family of regulatory proteins. It costimulates the proliferation of T cells, and mediates IFN gamma production. Ligation of CD273 on dendritic cells enhances dendritic cell activation and T cell responses. When interacting with CD279, it can act as a coinhibitor of the T cell function. CD273 expression is a useful marker to distinguish primary mediastinal B cell lymphoma from other diffuse large B cell lymphomas.
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Klon-Bezeichnung:
[24F.10C12]
Puffer:
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Target-Kategorie:
CD273
Anwendungsbeschreibung:
Flow cytometry: Recommended dilution: 1-5 µg/ml
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