Anti-Hu CD138 FITC, Clone: [MI15], Monoclonal

Artikelnummer: EXB-1F-814-T100
Artikelname: Anti-Hu CD138 FITC, Clone: [MI15], Monoclonal
Artikelnummer: EXB-1F-814-T100
Hersteller Artikelnummer: 1F-814-T100
Alternativnummer: EXB-1F-814-T100
Hersteller: EXBIO
Kategorie: Antikörper
Applikation: FC
Spezies Reaktivität: Human, Primate
Immunogen: A mixture of U266 and XG-1 human myeloma cell lines
Konjugation: FITC
CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
Klonalität: Monoclonal
Klon-Bezeichnung: [MI15]
Isotyp: Mouse IgG1 kappa
Puffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Lagerung: 2°C to 8°C
Target-Kategorie: CD138
Antibody Type: Monoclonal Antibody
Application Verdünnung: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Anwendungsbeschreibung: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.