Anti-Hu CD32 PE, Clone: [3D3], Monoclonal

Produktübersicht

• Artikelname: Anti-Hu CD32 PE, Clone: [3D3], Monoclonal
• Artikelnummer: EXB-1P-751-T100
• Hersteller Artikelnummer: 1P-751-T100
• Alternativnummer: EXB-1P-751-T100
• Hersteller: EXBIO
• Kategorie: Antikörper
• Applikation: FC
• Spezies Reaktivität: Human
• Immunogen: purified glycosylated recombinant human FcgammaRIIa2
• Konjugation: PE

Produktbeschreibung

CD32 (FcgammaRII) is a low affinity receptor for aggregated IgG. It is strongly expressed on monocytes, granulocytes, myeloid and myeloblastic cell lines, and weakly on B cells, CD34+ bone marrow cells, and resting and activated platelets. After binding its ligand, CD32 induces IgG-mediated phagocytosis and oxidative burst in monocytes and neutrophils, whereas in B cells it mediates a negative signal. This polymorphic transmembrane glycoprotein is expressed not only in the activating (CD32a) and inhibitory isoform (CD32b), but also in individual variants with differing avidities for IgG subtypes (e.g. the CD32a131R and CD32a131H allotypes).

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [3D3]
• Isotyp: Mouse IgG1 kappa
• Puffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Lagerung: 2°C to 8°C
• Target-Kategorie: CD32
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Application Verdünnung: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
• Anwendungsbeschreibung: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.