Anti-Hu CD112 PE, Clone: [R2.525], Monoclonal

Artikelnummer: EXB-1P-777-T100
Artikelname: Anti-Hu CD112 PE, Clone: [R2.525], Monoclonal
Artikelnummer: EXB-1P-777-T100
Hersteller Artikelnummer: 1P-777-T100
Alternativnummer: EXB-1P-777-T100
Hersteller: EXBIO
Kategorie: Antikörper
Applikation: FC
Spezies Reaktivität: Human
Immunogen: NIH/3T3 cells transfected with human Nectin-2
Konjugation: PE
CD112, also known as nectin-2, is a transmembrane glycoprotein involved in organization of adherens junctions. It also serves as a target molecule for entry of certain strains of herpes simplex virus (HSV) and pseudorabies virus (PRV). It is homologous to CD155, which serves as a target molecule for polio virus. CD112 seems to play a role in neural tube formation, with N-cadherin. Inside the cell, CD112 is connected with actin cytoskeleton through afadin. Variations in the CD112 gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Klonalität: Monoclonal
Klon-Bezeichnung: [R2.525]
Isotyp: Mouse IgG1 kappa
Puffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Lagerung: 2°C to 8°C
Target-Kategorie: CD112
Antibody Type: Monoclonal Antibody
Application Verdünnung: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Anwendungsbeschreibung: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.