Anti-Hu CD207 Alexa Fluor 647, Clone: [2G3], AF647, Monoclonal

Produktübersicht

• Artikelname: Anti-Hu CD207 Alexa Fluor 647, Clone: [2G3], AF647, Monoclonal
• Artikelnummer: EXB-A6-946-T100
• Hersteller Artikelnummer: A6-946-T100
• Alternativnummer: EXB-A6-946-T100
• Hersteller: EXBIO
• Kategorie: Antikörper
• Applikation: FC, ICC, IHC-Fr
• Spezies Reaktivität: Human, Primate
• Immunogen: Fusion protein of human CD207 extracellular part and IgG Fc fragment
• Konjugation: AF647

Produktbeschreibung

CD207 is a 40 kDa type II transmembrane glycoprotein of the C-type lectin family. It binds to mannose-bearing glycoproteins and glycolipids of microbial and viral antigens, including HIV gp120. CD207 is expressed only in Langerhans cells, which are immature dendritic cells of the epidermis and mucosa, and its expression decreases during Langerhans cells maturation. Upon antigen binding CD207 localizes to the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed membranes, which leads to a nonclassical antigen-processing pathway.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [2G3]
• Puffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Target-Kategorie: CD207

Anwendungsbeschreibung

• Anwendungsbeschreibung: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.