CD371, also known as CLEC12A, is a 30 kDa type II transmembrane glycoprotein of the C-type lectin family. Several alternatively spliced isoforms have been described. Using ITIM in its cytoplasmic part, this receptor serves as a negative regulator of CD371-positive cells, mainly granulocytes and monocytes, and is involved in dendritic cell maturation. It is one of markers of myeloid cells, including acute myeloid leukemia.
Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
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