Anti-Hu CD279 PerCP-Cy5.5, Clone: [EH12.2H7], Monoclonal

Produktübersicht

• Artikelname: Anti-Hu CD279 PerCP-Cy5.5, Clone: [EH12.2H7], Monoclonal
• Artikelnummer: EXB-T9-176-T100
• Hersteller Artikelnummer: T9-176-T100
• Alternativnummer: EXB-T9-176-T100
• Hersteller: EXBIO
• Kategorie: Antikörper
• Applikation: FC
• Spezies Reaktivität: Human, Primate
• Immunogen: recombinant human CD279
• Konjugation: PerCP/Cy5.5

Produktbeschreibung

CD279 / PD-1 (programmed cell death 1), a transmembrane protein of CD28/CTLA-4 family. It is expressed inducibly mainly on activated T, B, and myeloid cells and plays a role in maintaining peripheral self-tolerance. Binding to its ligands CD273 and CD274 is associated with inhibition of T cell proliferation and induction of their anergy. It is also expressed during thymic development. Some variants of CD279 are associated with susceptibility to systemic lupus erythematosus, type 1 diabetes, and rheumatoid arthritis.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [EH12.2H7]
• Isotyp: Mouse IgG1 kappa
• Puffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Lagerung: 2°C to 8°C
• Target-Kategorie: CD279
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Application Verdünnung: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
• Anwendungsbeschreibung: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.