BML-277, CAS [[516480-79-8]]

Produktübersicht

• Artikelname: BML-277, CAS [[516480-79-8]]
• Artikelnummer: FBM-10-1024
• Hersteller Artikelnummer: 10-1024
• Alternativnummer: FBM-10-1024-5MG, FBM-10-1024-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide

Produktbeschreibung

CHK2 inhibitor

Produkteigenschaften

• Molekulargewicht: 363.81
• Reinheit: 98% by TLC [50% ethyl acetate in hexanes, Rf = 0.17] NMR conforms
• Formulierung: Off-white solid
• CAS Nummer: [516480-79-8]
• Formel: C20H14ClN3O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent selective inhibitor of Chk2 (IC50 = 15 nM). BML-277 has been screened against a panel of 35 kinases, and shows less that 25% inhibition of any other kinase at 10 µM, demonstrating the selectivity1. Also displays radioprotective activity, preventing apoptosis in human T-cells that were subjected to ionizing radiation (EC50 = 3.0 - 7.6 µM).