ZM-336372, CAS [[208260-29-1]]

Produktübersicht

• Artikelname: ZM-336372, CAS [[208260-29-1]]
• Artikelnummer: FBM-10-1030
• Hersteller Artikelnummer: 10-1030
• Alternativnummer: FBM-10-1030-5MG, FBM-10-1030-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]benzamide

Produktbeschreibung

c-Raf inhibitor

Produkteigenschaften

• Molekulargewicht: 389.46
• Reinheit: 98% by TLC NMR conforms
• Formulierung: Off-white solid
• CAS Nummer: [208260-29-1]
• Formel: C23H23N3O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent and specific inhibitor of the protein kinase c-Raf (IC50=70nM). Has no significant effect on many other protein kinases tested (even at 50µM) with the exception of p38 (SAPK2alpha) (IC50=2µM) and SAPK2beta (p38beta) (IC50=2µM). Induces a paradoxical >100-fold activation of c-Raf in whole cells. Induces apoptosis in a variety of cell lines. Cell permeable.