Mirin, CAS [[299953-00-7]]

Produktübersicht

• Artikelname: Mirin, CAS [[299953-00-7]]
• Artikelnummer: FBM-10-1069
• Hersteller Artikelnummer: 10-1069
• Alternativnummer: FBM-10-1069-5MG, FBM-10-1069-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one

Produktbeschreibung

Mre11-Rad50-Nbs1 inhibitor

Produkteigenschaften

• Molekulargewicht: 220.25
• Reinheit: 98% by TLC, NMR Conforms
• Formulierung: Tan solid
• CAS Nummer: [299953-00-7]
• Formel: C10H8N2O2S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Mirin is an inhibitor of the Mre11-Rad50-Nbs1(MRN) complex (IC50 = 12 µM for inhibition of ATM activity), part of the MRN-ATM(ataxia-telangiectasia mutated) pathway, an essential pathway for sensing and signaling from DNA double-strand breaks. Mirin abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells.