Chemical Name: 4,5-Diphenyl-2-oxazolepropanoic acid
NFkappaB inhibitor
Molekulargewicht:
293.32
Reinheit:
98% by TLC, NMR Conforms
Formulierung:
White solid
CAS Nummer:
[21256-18-8]
Formel:
C18H15NO3
Anwendungsbeschreibung:
Oxaprozin is a clinically useful non-steroidal anti-inflammatory drug.1 In addition to typical NSAID COX inhibition, Oxaprozin may also exert anti-inflammatory effects via inhibition of the Akt/IKK/NF-kappabeta pathway.2 The compound is capable of inhibiting both anandamide hydrolase in neurons (IC50= 85 µmol/l), with consequent potent analgesic activity, and NF-kappaB activation in inflammatory cells (IC50 = 50 µmol/l).3
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten