Chemical Name: (R)-(-)-N-alpha-Dimethyl-N-2-propynylbenzeneethanamine, hydrochloride. Alternate Names: Selegiline
MAO-B inhibitor
Molekulargewicht:
223.74
Reinheit:
98% by TLC, NMR (Conforms)
Formulierung:
White solid
CAS Nummer:
[14611-52-0]
Formel:
C13H17NHCl
Anwendungsbeschreibung:
Potent inhibitor of monoamine oxidase B (MAO- B) which has been used for the treatment of Parkinsons disease.1,2 Displays neuroprotective effects rescuing nigral dopaminergic neurons after systemic MPTP treatment.3 Rescues PC12 cells from trophic withdrawal-induced apoptosis.4 Glyceraldehyde-3-phosphate dehydrogenase has been found to be the putative target responsible for its neuroprotective effects.5
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