Chemical Name: 4-[(4-hydroxyphenyl)amino]-6,7-dimehtoxyquinazoline. Alternate Names: JANEX-1
JAK3 inhibitor
Molekulargewicht:
333.78
Reinheit:
98% by TLC, NMR (conforms)
Formulierung:
Yellow solid
CAS Nummer:
[202475-60-3]
Formel:
C16H15N3O3 HCl
Anwendungsbeschreibung:
JAK3 inhibitor. Inhibits human glioblastoma cell adhesion and invasion.1 Increases survival in a mouse ALS model.2 Delays or prevents autoimmune type 1 diabetes in NOD mice.3 Exhibits potent anti-inflammatory activity in mouse models of peritonitis, colitis, cellulitis and systemic inflammatory response syndrome.4 Displays protective effects against myocardial ischemia and reperfusion injury in mouse models.5
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