ODQ, CAS [[41443-28-1]]

Produktübersicht

• Artikelname: ODQ, CAS [[41443-28-1]]
• Artikelnummer: FBM-10-1211
• Hersteller Artikelnummer: 10-1211
• Alternativnummer: FBM-10-1211-5MG, FBM-10-1211-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one

Produktbeschreibung

Soluble guanylyl cyclase inhibitor

Produkteigenschaften

• Molekulargewicht: 187.15
• Reinheit: 98% by HPLC NMR (conforms)
• Formulierung: Pale-yellow solid
• CAS Nummer: [41443-28-1]
• Formel: C9H5N3O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: A potent and selective inhibitor of soluble guanylyl cyclase (sGC), IC50 = 20 nM).1 ODQ acts via competition with NO for the heme site of sGC where it binds irreversibly.2 ODQ does not inhibit NO-mediated macrophage toxicity, an activity that is unrelated to cGMP nor does it inhibit particulate GC.1 ODQ is an extremely useful tool to explore the involvement of the NO-cGMP pathway in cellular signaling and physiologic processes.3-5