CHIR-99021, CAS [[252917-06-9]]

Produktübersicht

• Artikelname: CHIR-99021, CAS [[252917-06-9]]
• Artikelnummer: FBM-10-1279
• Hersteller Artikelnummer: 10-1279
• Alternativnummer: FBM-10-1279-5MG, FBM-10-1279-25MG, FBM-10-1279-10MM/1MLDMSO
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile

Produktbeschreibung

GSK3beta inhibitor

Produkteigenschaften

• Molekulargewicht: 465.35
• Reinheit: 99% by TLC, NMR (conforms)
• Formulierung: Tan solid
• CAS Nummer: [252917-06-9]
• Formel: C22H18Cl2N8

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent and selective inhibitor of glycogen synthase kinase-3beta (GSK3beta, IC50 = 5 nM) and GSK3alpha (IC50 = 10 nM)1. Induces osteoblastogenesis, increases mineralization and inhibits adipogenesis in ST2 cells2. Promotes replication and survival of pancreatic beta cells3. Enhances differentiation and reduces proliferation of adult human olfactory epithelium neural precursors4. Cell permeable and active in vivo.