Garcinol, CAS [[78824-30-3]]

Produktübersicht

• Artikelname: Garcinol, CAS [[78824-30-3]]
• Artikelnummer: FBM-10-1337
• Hersteller Artikelnummer: 10-1337
• Alternativnummer: FBM-10-1337-10MG,FBM-10-1337-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

HAT inhibitor

Produkteigenschaften

• Molekulargewicht: 602.80
• Reinheit: >95%
• Formulierung: Yellow solid
• CAS Nummer: [78824-30-3]
• Formel: C38H50O6

Anwendungsbeschreibung

• Anwendungsbeschreibung: Garcinol is a HAT (histone acetyltransferase) inhibitor (p300 IC50=7µM and PCAF IC50=5µM) both in vitro and in vivo.1 It potentiates TRAIL-induced apoptosis of cancer cells. Garcinol, independent of the cell type, induces both of the TRAIL receptors, death receptor 4 (DR4) and DR5. Garcinol neither induces the receptors of normal cells nor sensitizes them to TRAIL.2