NSC663284, CAS [[383907-43-5]]

Produktübersicht

• Artikelname: NSC663284, CAS [[383907-43-5]]
• Artikelnummer: FBM-10-1352
• Hersteller Artikelnummer: 10-1352
• Alternativnummer: FBM-10-1352-5MG, FBM-10-1352-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 6-Chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione

Produktbeschreibung

Cdc25 phosphatase inhibitor

Produkteigenschaften

• Molekulargewicht: 321.77
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Red solid
• CAS Nummer: [383907-43-5]
• Formel: C15H16ClN3O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent, selective and irreversible inhibitor of CDC25 phosphatases, Ki=29, 95 and 89 nM for human CDC25A, B2 and C respectively and >20- and >450-fold selective over VHR and PTP1B1. Arrests cells at G1 and G2/M and inhibits cdk1 and 2 activation2. Inhibits the growth of a variety of human tumor cell lines3. Acts via irreversible oxidation of the catalytic cysteine of CDC254.