FQI1, CAS [[599151-35-6]]

Produktübersicht

• Artikelname: FQI1, CAS [[599151-35-6]]
• Artikelnummer: FBM-10-1360
• Hersteller Artikelnummer: 10-1360
• Alternativnummer: FBM-10-1360-5MG, FBM-10-1360-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 8-(2-Ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinoline-6(5H)-one

Produktbeschreibung

LSF inhibitor

Produkteigenschaften

• Molekulargewicht: 311.33
• Reinheit: 98% by TLC NMR (conforms)
• Formulierung: White solid
• CAS Nummer: [599151-35-6]
• Formel: C18H17NO4

Anwendungsbeschreibung

• Anwendungsbeschreibung: Inhibitor of transcription factor LSF specifically targeting its DNA binding and corresponding transcriptional activity (IC50=2.1 M). Rapidly induces apoptosis in an aggressive hepatocellular carcinoma (HCC) cell line and dramatically inhibits tumor growth in a mouse xenograft model with no general tissue cytotoxicity.1,2 In human HCC cells, FQI1 induced mitotic arrest with an accompanying increase in cyclin B1.3 Blocks LSF-stimulated activation of DNA methyltransferase 1.4 Cell permeable.