Chemical Name: N-[2-Hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidamide, dihydrochloride
Cellular protectant
Molekulargewicht:
351.28
Reinheit:
>98% by TLC, NMR (conforms)
Formulierung:
Off-white solid
CAS Nummer:
[66611-37-8]
Formel:
C14H22N4O22HCl
Anwendungsbeschreibung:
Cellular protectant operating by several mechanisms. It is an insulin sensitizer1, HSP72 activator2, PARP inhibitor and ROS and lipid peroxidation reducer3. It protects mitochondria in acetaminophen-induced liver injury4 as well as LPS-induced destabilization5 and activates mitochondrial fusion6. Displays protective effects in heart failure7 and traumatic brain injury8 in animal models.
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