Ferrostatin-1, CAS [[347174-05-4]]

Artikelnummer: FBM-10-1380
Artikelname: Ferrostatin-1, CAS [[347174-05-4]]
Artikelnummer: FBM-10-1380
Hersteller Artikelnummer: 10-1380
Alternativnummer: FBM-10-1380-5MG,FBM-10-1380-25MG,FBM-10-1380-10MM/1MLDMSO
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Ferroptosis inhibitor
Molekulargewicht: 262.35
Reinheit: 98% by TLC, NMR (conforms)
Formulierung: Tan solid
CAS Nummer: [347174-05-4]
Formel: C15H22N2O2
Anwendungsbeschreibung: Inhibits ferroptosis (EC50=60 nM), an iron-dependent form of nonapoptotic cell death1. Potent inhibitor of ferroptosis in cancer cells and glutamate-induced cell death in organotypic rat brain slices1. Blocks the cytotoxic effects of sorafenib in hepatocellular carcinoma cells2. Inhibits oxidative lipid damage and cell death in diverse disease models3. Prevents apoptosis of renal proximal tubular cells induced by reactive oxygen species4.