Borrelidin, CAS [[7184-60-3]]

Produktübersicht

• Artikelname: Borrelidin, CAS [[7184-60-3]]
• Artikelnummer: FBM-10-1399
• Hersteller Artikelnummer: 10-1399
• Alternativnummer: FBM-10-1399-1MG, FBM-10-1399-5MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: Fermentation from Streptomyces sp. Alternate Names: U-78548, C2989, Treponemycin

Produktbeschreibung

Angiogenesis inhibitor

Produkteigenschaften

• Molekulargewicht: 489.66
• Reinheit: 98% by HPLC, NMR (conforms)
• Formulierung: Off-white solid
• CAS Nummer: [7184-60-3]
• Formel: C28H43NO6

Anwendungsbeschreibung

• Anwendungsbeschreibung: Novel macrolide which inhibits bacterial and eukaryotic threonyl-tRNA synthetase.1 Displays potent anti-angiogenic activity (IC50=0.8 nM) and induces the collapse of newly formed capillary tubules.2 Modulates alternative splicing of VEGF in favor of anti-angiogenic isoforms.3 Induces apoptosis in ALL cell lines.4 Induces unfolded protein response in oral cancer cells.5 Cell permeable.