AK-7, CAS [[420831-40-9]]

Produktübersicht

• Artikelname: AK-7, CAS [[420831-40-9]]
• Artikelnummer: FBM-10-1429
• Hersteller Artikelnummer: 10-1429
• Alternativnummer: FBM-10-1429-5MG, FBM-10-1429-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3-(1-Azepanylsulfonyl)-N-(3-bromophenyl)benzamide

Produktbeschreibung

SIRT2 inhibitor

Produkteigenschaften

• Molekulargewicht: 437.36
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [420831-40-9]
• Formel: C19H21BrN2O3S

Anwendungsbeschreibung

• Anwendungsbeschreibung: A selective Sirt2 inhibitor (IC50=15.5 µM) which does not inhibit Sirt1 or Sirt31. It down regulates cholesterol biosynthesis genes in primary striatal neurons1. Displays neuroprotective effects in Huntingtons disease mouse models including improved motor function, extended survival and reduced brain atrophy all of which were associated with reduced aggregated mutant huntingtin2.