HTS01037, CAS [[682741-29-3]]

Produktübersicht

• Artikelname: HTS01037, CAS [[682741-29-3]]
• Artikelnummer: FBM-10-1453
• Hersteller Artikelnummer: 10-1453
• Alternativnummer: FBM-10-1453-5MG, FBM-10-1453-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-[(3-Carboxy-1-oxo-2-propen-1-yl)amino]-[2,2-bithiophene]-5-carboxylic acid, 5-methyl ester

Produktbeschreibung

FABP inhibitor

Produkteigenschaften

• Molekulargewicht: 337.37
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [682741-29-3]
• Formel: C14H11NO5S2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Inhibits fatty acid binding proteins. Inhibits lipolysis in 3T3-L1 adipocytes and reduces LPS-stimulated inflammation in cultured macrophages. Acts as an antagonist of the protein-protein interaction between AFABP/aP2 and hormone sensitive lipase but does not activate PPARgamma in macrophages1. Inhibits FABP-dependent and fatty acid-stimulated leukotriene C4 biosynthesis2. Reduces intracellular free fatty acid levels, lowering macrophage inflammation and ER stress3. Reduces LPS-stimulated IL-1beta secretion in a mouse model4. Inhibits VLDL-induced foam cell formation5.