Salirasib, CAS [[162520-00-5]]

Produktübersicht

• Artikelname: Salirasib, CAS [[162520-00-5]]
• Artikelnummer: FBM-10-1461
• Hersteller Artikelnummer: 10-1461
• Alternativnummer: FBM-10-1461-5MG,FBM-10-1461-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Ras inhibitor

Produkteigenschaften

• Molekulargewicht: 358.54
• Reinheit: >98% by TLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [162520-00-5]
• Formel: C22H30O2S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Salirasib is a synthetic farnesylcysteine mimetic that inhibits ras proteins1,2 via disruption of interactions between the S-Prenyl moiety of Ras and the membrane anchorage domains3. It has been investigated in the treatment of various cancers.4,5 HCC cells pretreated with salirasib were sensitized to TRAIL-induced apoptosis.6 Salirasib has also been shown to inhibit TRPA1 (EC50 = 1.3 µM).7