LY364947, CAS [[396129-53-6]]

Produktübersicht

• Artikelname: LY364947, CAS [[396129-53-6]]
• Artikelnummer: FBM-10-1492
• Hersteller Artikelnummer: 10-1492
• Alternativnummer: FBM-10-1492-5MG, FBM-10-1492-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinolone. Alternate Names: HTS-466284

Produktbeschreibung

ALK5 inhibitor

Produkteigenschaften

• Molekulargewicht: 272.31
• Reinheit: 98% by TLC
• Formulierung: Beige solid
• CAS Nummer: [396129-53-6]
• Formel: C17H12N4

Anwendungsbeschreibung

• Anwendungsbeschreibung: Selective ALK5 inhibitor, IC50 = 59, 400 and 1400 nM for TGF-beta RI, TGF-beta RII and MLK-7K, respectively1. Inhibits Smad2 phosphorylation induced by TGF-beta as well as fibronectin expression and MDA-MB-231 cell invasion2. Abolishes resistance of glioblastoma-initiating cells to radiation3. Cell permeable.