SRPIN340, CAS [[218156-96-8]]

Produktübersicht

• Artikelname: SRPIN340, CAS [[218156-96-8]]
• Artikelnummer: FBM-10-1500
• Hersteller Artikelnummer: 10-1500
• Alternativnummer: FBM-10-1500-5MG,FBM-10-1500-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

SRPK inhibitor

Produkteigenschaften

• Molekulargewicht: 349.35
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [218156-96-8]
• Formel: C18H18F3N3O

Anwendungsbeschreibung

• Anwendungsbeschreibung: Selective serine arginine protein kinase (SRPK) 1 inhibitor (Ki = 0.89 µM).1 Inhibits SRPK2 at higher concentrations. Does not significantly inhibit other SRPKs such as CLK1 and CLK4, or other classes of SR kinases. Inhibits viral replication by inhibition of host SR protein kinases.1 Modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy2 and controls VEGF-mediated tumor angiogenesis in xenografts3.