NSC33994, CAS [[82058-16-0]]

Produktübersicht

• Artikelname: NSC33994, CAS [[82058-16-0]]
• Artikelnummer: FBM-10-1530
• Hersteller Artikelnummer: 10-1530
• Alternativnummer: FBM-10-1530-5MG,FBM-10-1530-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: G6

Produktbeschreibung

JAK2 inhibitor

Produkteigenschaften

• Molekulargewicht: 436.65
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [82058-16-0]
• Formel: C28H42N2O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: A remarkably potent and selective JAK2 inhibitor (IC50 = 60 nM). Displays no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 µM1. Suppresses JAK2-V617F-mediated human pathological cell growth in vitro and in vivo2 and is concomitant with the disruption of intracellular vimentin filaments3. Reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo4.