Exo2, CAS [[304684-77-3]]

Produktübersicht

• Artikelname: Exo2, CAS [[304684-77-3]]
• Artikelnummer: FBM-10-1594
• Hersteller Artikelnummer: 10-1594
• Alternativnummer: FBM-10-1594-5MG, FBM-10-1594-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2-Methoxy-4-[(5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol

Produktbeschreibung

GBF1 inhibitor, induces Golgi disassembly

Produkteigenschaften

• Molekulargewicht: 354.43
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [304684-77-3]
• Formel: C18H18N4O2S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Exo2 disrupts the Golgi apparatus and stimulates Golgi-ER fusion in mammalian cells.1 May be used to completely ablate the Golgi apparatus.1 Like brefeldin A (BFA), it inhibits anterograde transport and disrupts morphology of the trans-Golgi network (TGN) but unlike BFA, it does not induce tubulation and merging of the TGN and endosomal compartments.2 It perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network, in contrast to cholera toxin.1,2 Accelerates degradation of perilipin-2 proteins.3