Manidipine dihydrochloride, CAS [[89226-75-5]]

Produktübersicht

• Artikelname: Manidipine dihydrochloride, CAS [[89226-75-5]]
• Artikelnummer: FBM-10-2045
• Hersteller Artikelnummer: 10-2045
• Alternativnummer: FBM-10-2045-20MG,FBM-10-2045-100MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: CV-40932HCl, Franidipine2HCl

Produktbeschreibung

Calcium channel blocker / SARS-CoV2 3CLpro inhibitor

Produkteigenschaften

• Molekulargewicht: 683.63
• Reinheit: 98% by HPLC NMR (conforms)
• Formulierung: White solid
• CAS Nummer: [89226-75-5]
• Formel: C35H38N4O62HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: Manidipine is a clinically useful antihypertensive.1,2 It is an inhibitor of L- and T-type calcium channels with high selectivity for vasculature. Manidipine has recently been found to be an inhibitor (IC50 = 4.8 µM) of the SARS-CoV-2 main protease, 3CLpro.3 It also acts as an early entry inhibitor of human cytomegalovirus (EC50 = 3.57 µM) via inhibition of the Immediate-Early 2 (IE2) protein.4