Candesartan, CAS [[139481-59-7]]

Produktübersicht

• Artikelname: Candesartan, CAS [[139481-59-7]]
• Artikelnummer: FBM-10-2049
• Hersteller Artikelnummer: 10-2049
• Alternativnummer: FBM-10-2049-50MG,FBM-10-2049-250MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: CV-11974

Produktbeschreibung

Angiotensin II antagonist

Produkteigenschaften

• Molekulargewicht: 400.45
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [139481-59-7]
• Formel: C24H20N6O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: Angiotensin II receptor I (AT1) antagonist, IC50s=1.12 and 2.86 nM for bovine adrenal cortex and rabbit aorta respectively.1 Selectively inhibits angiotensin II-induced contraction of rabbit aortic strips with no effect on contraction induced by other agents such as norepinephrine, KCl, serotonin, PGF2alpha or endothelin. Prevents astrocyte and microglial activation and neuroinflammation and improves hippocampal neurogenesis.2 Attenuates angiogenesis in hepatocellular carcinoma.3 Clinically useful antihypertensive agent. Ameliorates brain inflammation associated with Alzheimers disease.4 Active in vivo and orally active.