Picropodophyllotoxin, CAS [[477-47-4]]

Produktübersicht

• Artikelname: Picropodophyllotoxin, CAS [[477-47-4]]
• Artikelnummer: FBM-10-2189
• Hersteller Artikelnummer: 10-2189
• Alternativnummer: FBM-10-2189-5MG,FBM-10-2189-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

IGF1R inhibitor

Produkteigenschaften

• Molekulargewicht: 414.42
• Reinheit: 97% by TLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [477-47-4]
• Formel: C22 H22 O8

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF1R) which is non-competitive with ATP1. Displays no activity at IR, EGFR, FGFR or PDGFR. Inhibits IGF1R autophosphorylation IC50 ~ 1 nM1. Displays antiproliferative activity in numerous tumor cell lines, IC50 = 0.05 - 15 M2. Exhibits antiangiogenic activitiy3. Attenuates intimal hyperplasia after vascular injury4. Active in vivo.