Chemical Name: (2Z)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]-carbonyl]amino]-2-heptenoic acid, sodium salt. Alternate Names: MK 0791
Protease inhibitor
Molekulargewicht:
380.43
Reinheit:
98% by TLC, NMR (Conforms)
Formulierung:
White solid
CAS Nummer:
[81129-83-1]
Formel:
C16H25N2O5S Na
Anwendungsbeschreibung:
Dehydropeptidase-1 inhibitor. Inhibits the proteolytic conversion of leukotriene D4 to E4.1 Inhibits the mammalian beta-lactamase renal dipeptidase (dehydropeptidase-1, DPEP1) and thus is used as an antibacterial adjunct to extend the half-life of beta-lactam antibiotics.2 Cilastatin also inhibits bacterial metallo-beta-lactamase and thereby may block resistance to the carbapenem family of antibiotics in certain bacteria.3 Suppresses invasion and metastasis of DPEP1-expressing tumor cells.4
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