Ibudilast, CAS [[50847-11-5]]

Produktübersicht

• Artikelname: Ibudilast, CAS [[50847-11-5]]
• Artikelnummer: FBM-10-2236
• Hersteller Artikelnummer: 10-2236
• Alternativnummer: FBM-10-2236-5MG, FBM-10-2236-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine. Alternate Names: 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridine-3-yl 1-propanone, KC-404, AV411

Produktbeschreibung

Neuroinflammation inhibitor (PDE pan-inhibitor)

Produkteigenschaften

• Molekulargewicht: 230.31
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [50847-11-5]
• Formel: C14H18N2O

Anwendungsbeschreibung

• Anwendungsbeschreibung: Phosphodiesterase inhibitor with some selectivity for PDE4 and 5. (IC50s= 53, 35, 48,12 and10 µM for PDE 1a, 2, 3, 4 and 5 respectively1). Acts as a cerebral vasodilator by selectively inducing a cGMP-independent relaxation of the intracranial vertebrobasilar artery.2 Attenuates neuroinflammation and enhances retinal ganglion cell viability in glaucoma via PKA signaling.3 A glial cell activation inhibitor.4 Enhances morphine analgesia and attenuates tolerance and withdrawaI.5 Orally active and crosses the blood-brain barrier.5