Chemical Name: 2-Butyl-4-chloro-1-{[2-(1H-tetrazol-5-yl)(1,1-biphenyl)-4-yl]methyl}-1H-imidazole-5-methanol, potassium salt. Alternate Names: DUP-753
Angiotensin AT1 antagonist
Molekulargewicht:
461.01
Reinheit:
99% by TLC, NMR (Conforms)
Formulierung:
Off-white solid
CAS Nummer:
[124750-99-8]
Formel:
C22H22ClKN6O
Anwendungsbeschreibung:
Non-peptide angiotensin II receptor antagonist.1,2 Clinically useful antihypertensive agent.3 Inhibits collagen I synthesis.4 Induces SIRT1 expression and activity and reduces hepatic injury in a rat reduced-size orthotopic liver transplantation model.5 Displays neuroprotective effects along with nimesulide against chronic fatigue stress.6 Displays myocardial antifibrotic activity.7
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