Pirfenidone, CAS [[53179-13-8]]

Produktübersicht

• Artikelname: Pirfenidone, CAS [[53179-13-8]]
• Artikelnummer: FBM-10-2307
• Hersteller Artikelnummer: 10-2307
• Alternativnummer: FBM-10-2307-10MG, FBM-10-2307-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 5-Methyl-1-phenyl-2(1H)-pyridinone

Produktbeschreibung

Antifibrotic

Produkteigenschaften

• Molekulargewicht: 185.23
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [53179-13-8]
• Formel: C12H11NO

Anwendungsbeschreibung

• Anwendungsbeschreibung: Antifibrotic agent. Prevents lung fibrosis in bleomycin-induced animal models.1 Down-regulates bleomycin-induced overexpression of lung procollagen I and III genes.2 Up-regulates RGS2 (Regulator of G-protein Signaling 2) which represents a new mechanism of pirfenidone action.3 Inhibits fibroblast proliferation.4 Suppresses TNFalpha production at the translational level.5 Scavenges hydroxyl radicals and inhibits lipid peroxidation in a dose-dependent manner.6 Recently approved therapeutic agent for idiopathic pulmonary fibrosis.7 Orally active.