Chemical Name: 3,5-Dimethyl-tricyclo[3.3.1.13,7]decam-1-amine HCl. Alternate Names: 3,5-Dimethyl-tricyclo[3.3.1.13,7]decam-1-amine HCl
NMDA antagonist / Anti-Alzheimers
Molekulargewicht:
215.76
Reinheit:
98% by TLC, NMR (conforms)
Formulierung:
White solid
CAS Nummer:
[41100-52-1]
Formel:
C12H21N HCl
Anwendungsbeschreibung:
An NMDA noncompetitive, low affinity, open channel blocker, IC50~1 µM at -60 mV in rat retinal ganglion cells.1 Displays neuroprotective effects in excitotoxic conditions.2 Preferentially blocks excessive NMDA receptor activity without disrupting normal activity.3 A clinically well tolerated drug with therapeutic potential in numerous CNS degenerative disorders.4 In clinical use for Alzheimers disease.5
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