Chemical Name: 5-Deoxy-5-(1,4-diamino-4-carboxybutyl)adenosine. Alternate Names: A-9145, Adenosylornithine, Antibiotic 32232RP
Methyltransferase inhibitor
Molekulargewicht:
381.39
Reinheit:
>98% by HPLC NMR (Conforms)
Formulierung:
Tan solid
CAS Nummer:
[58944-73-3]
Formel:
C15H23N7O5
Anwendungsbeschreibung:
Nucleoside S-adenosyl-1-methionine analog. Potent, competitive methyltransferase (protein, DNA, and RNA methyltransferases) inhibitor1,2. IC50 < 1.0 and 2.5 µM for PRMT1 and SET7/9, respectively3. Binds with greater affinity to the adenine-specific DNA methyltransferase M.TaqI than S-adenosyl-L-homocysteine4. Inhibits biofilm formation by Streptococcus pneumoniae5.
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