CUDC-101, CAS [[1012054-59-9]]

Produktübersicht

• Artikelname: CUDC-101, CAS [[1012054-59-9]]
• Artikelnummer: FBM-10-2491
• Hersteller Artikelnummer: 10-2491
• Alternativnummer: FBM-10-2491-5MG,FBM-10-2491-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Dual HDAC and EGFR inhibitor

Produkteigenschaften

• Molekulargewicht: 434.49
• Reinheit: 99% by HPLC NMR (Conforms)
• Formulierung: White or off-white solid
• CAS Nummer: [1012054-59-9]
• Formel: C24H26N4O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: A novel hybrid dual-acting HDAC and receptor tyrosine kinase inhibitor. It is a potent HDAC inhibitor which also inhibits EGFR and HER2, IC50 = 4.4, 2.4 and 15.7 nM respectively.1 It not only blocks EGFR and HER2 but also attenuates multiple compensatory pathways such as AKT, HER3 and MET which enable tumor cells to escape the effects of conventional EGFR/HER2 inhibitors.1,2