Chemical Name: 2,3-Dimethoxy-5-methyl-6-decyl-1,4-benzoquinone
MPTP inhibitor
Molekulargewicht:
322.44
Reinheit:
97% by HPLC NMR (Conforms)
Formulierung:
Yellow/Orange Oil
CAS Nummer:
[55486-00-5]
Formel:
C19H30O4
Anwendungsbeschreibung:
Inhibits the Ca2+ dependent mitochondrial permeability transition pore (MPTP) without inhibiting respiration.1 Maximum effect on Ca2+ retention capacity of rat liver mitochondria at 100 µM. Inhibits etoposide-induced apoptosis in in L929 cells at 5 µM via inhibition of cytochrome c release.2 Delays rotenone-induced cardiac dysfunction in a zebrafish model of development and cardiovascular function.3 Substrate for various quinone oxidoreductases.4,5
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