Swainsonine, CAS [[72741-87-8]]

Produktübersicht

• Artikelname: Swainsonine, CAS [[72741-87-8]]
• Artikelnummer: FBM-10-2674
• Hersteller Artikelnummer: 10-2674
• Alternativnummer: FBM-10-2674-1MG, FBM-10-2674-5MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (1S,2R,8R,8aR)-octahydro-1,2,8-indolizinetriol

Produktbeschreibung

Glycosidase inhibitor

Produkteigenschaften

• Molekulargewicht: 173.21
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: White or off-white solid
• CAS Nummer: [72741-87-8]
• Formel: C8H15NO3

Anwendungsbeschreibung

• Anwendungsbeschreibung: A naturally occurring alkaloidal toxin found in locoweed. Inhibits the biosynthesis of complex glycoproteins by inhibition of Golgi mannosidase II (IC50 = 0.2 µM).1 Inhibits growth and potentiates the cytotoxic effect of taxol in hepatocellular carcinoma in vivo.2 Induces apoptosis in a variety of cell types including cerebral cortical neurons.3 Impairs adult neurogenesis and spatial learning and memory.4 Abrogation of complex glycosylation by swainsonine results in strain-and cell-specific inhibition of prion replication.5 Induces lysosomal storage disease in farm animals.6