Chemical Name: N-(3-Methoxy-4-hydroxy-benzyl)-arachidonamide. Alternate Names: Vanillylarachidonamide
TRPV1 channel activator
Molekulargewicht:
439.64
Reinheit:
>98% by TLC, NMR (Conforms)
Formulierung:
Colorless or slightly yellow viscous oil
CAS Nummer:
[128007-31-8]
Formel:
C28H41NO3
Anwendungsbeschreibung:
Arvanil is a non-pungent capsaicin analog with antinociceptive and anti-inflammatory effects in vivo.1 It is an agonist at TRPV1 as well as CB1 (Ki = 0.25 - 0.52 µM), but not CB2.2,3 Caused high mitochondrial calcium flow in hepatocellular carcinoma cells, ultimately leading to ferroptosis.4 It induced FADD-dependent apoptosis in lymphoid Jurkat T-cells.5 Neuroprotective in rat excitotoxicity model.6
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