Chemical Name: (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid. Alternate Names: Argidipine, MQPA
Thrombin inhibitor
Molekulargewicht:
508.63
Reinheit:
99% by HPLC NMR (Conforms)
Formulierung:
White solid
CAS Nummer:
[74863-84-6]
Formel:
C23H36N6O5S
Anwendungsbeschreibung:
Potent and selective thrombin inhibitor (Ki = 19 nM)1. Prevents platelet-rich arterial thrombosis in a rabbit model2. Ameliorates early brain injury and improves neurological outcomes after subarachnoid hemorrhage in a rat model3. Reduces breast cancer malignancy and metastasis via osteopontin-dependent and independent mechanisms4.
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