Chemical Name: 4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione
Nrf2 activator
Molekulargewicht:
226.34
Reinheit:
98% by TLC, NMR (Conforms)
Formulierung:
Red solid
CAS Nummer:
[64224-21-1]
Formel:
C8H6N2S3
Anwendungsbeschreibung:
Upregulates the transcription factor NRF2 and prevents insulin resistance and obesity induced by high fat diet in C57BL/6J mice1. Attenuates the progression of fibrosis in a rat model of nonalcoholic steatohepatitis2. Attenuates chronic hypoxia-induced cardiopulmonary alterations in mice3. Promotes liver regeneration after partial hepatectomy4. Off target effects: Activates constitutive androstane receptor (CAR)5.
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