Obeticholic acid, CAS [[459789-99-2]]

Produktübersicht

• Artikelname: Obeticholic acid, CAS [[459789-99-2]]
• Artikelnummer: FBM-10-2838
• Hersteller Artikelnummer: 10-2838
• Alternativnummer: FBM-10-2838-10MG,FBM-10-2838-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3alpha-7alpha-dihydroxy-6alpha-ethyl-5ß-cholan-24-oic acid. Alternate Names: 6-ECDCA, 6-Ethylchenodeoxycholic acid

Produktbeschreibung

FXR agonist

Produkteigenschaften

• Molekulargewicht: 420.63
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [459789-99-2]
• Formel: C26H44O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: A novel cholic acid analog which acts as a potent and selective FXR agonist (EC50= 99 nM). Displays anticholeretic activity in a rat model of cholestasis.1 Promotes adipocyte differentiation and regulates adipose cell function.2 Normalizes insulin sensitivity in a rabbit model of metabolic syndrome.3 A potentially new therapeutic agent for management of non-alcoholic fatty liver disease4 and NASH5. Displays therapeutic benefit in patients with primary biliary cirrhosis.6 Active in vivo.

Bilder

10-2838