Saracatinib, CAS [[379231-04-6]]

Produktübersicht

• Artikelname: Saracatinib, CAS [[379231-04-6]]
• Artikelnummer: FBM-10-2901
• Hersteller Artikelnummer: 10-2901
• Alternativnummer: FBM-10-2901-5MG, FBM-10-2901-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine. Alternate Names: AZD0530

Produktbeschreibung

Src family kinase inhibitor

Produkteigenschaften

• Molekulargewicht: 542.03
• Reinheit: >98% HPLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [379231-04-6]
• Formel: C27H32ClN5O5

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent and selective inhibitor of Src family kinases, IC50=4-10 nM for Src, c-Yes, Fyn, Lyn, Blk, Fgr and Lck.1 Demonstrates potent antimigratory, anti-invasive and antiproliferative activity and inhibits metastasis in a mouse model of bladder cancer.2 Inhibits MERS- CoV at early stages of the viral life cycle at mM concentrations.3,4 Rescues memory performance and reduces phospho-Tau accumulation in traumatic tauopathy.5 Rescues memory deficits and synaptic depletion in an Alzheimers mouse model.6