Chemical Name: Natural product isolated from Phomopsis sp. Alternate Names: NSC381839
Microtubule binding agent
Molekulargewicht:
789.24
Reinheit:
>98% by HPLC, NMR (Conforms)
Formulierung:
White or off-white solid
CAS Nummer:
[64925-80-0]
Formel:
C36H45ClN6O12
Anwendungsbeschreibung:
Phomopsin A is a novel fungal metabolite produced by Phomopsis sp. which may contaminate food and feed stocks.1 It binds to tubulin at the vinca site.2,3 Phomopsin interferes with intracellular transport, inhibits eukaryotic cell proliferation, and promotes cell death by suppressing microtubule dynamics.4
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