GW3965 HCl, CAS [[405911-17-3]]

Produktübersicht

• Artikelname: GW3965 HCl, CAS [[405911-17-3]]
• Artikelnummer: FBM-10-3069
• Hersteller Artikelnummer: 10-3069
• Alternativnummer: FBM-10-3069-5MG,FBM-10-3069-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

LXR agonist

Produkteigenschaften

• Molekulargewicht: 618.52
• Reinheit: >98% by HPLC (NMR Conforms)
• Formulierung: White solid
• CAS Nummer: [405911-17-3]
• Formel: C33H31ClF3NO3 HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: GW3965 is a potent and selective LXR agonist, activating human LXRalpha and beta in cell-based reporter gene assays (EC50=190 and 30 nM respectively).1 Since LXR is a master regulator of cholesterol and fatty acid metabolism, GW3965 exerts a variety of effects including antiatherosclerotic2, antiinflammatory3 as well as antinociceptive4 and alteration of fat tissue distribution5. Orally active.